Figure 1
From: PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein
PAX8 is expressed in RCC and adult normal kidney tissues. PAX8 expression was analyzed in 10 RCC sections and their normal kidney counterparts (cortex and medulla). Staining was consistently observed in the RCC cells, as well as in the cortex and medulla of adult kidney. A representative set is presented here. Abbreviations: PCT, proximal convoluted tubule; DCT, distal convoluted tubule; BC, Bowman's capsule; CD, collecting duct; RCC, renal cell carcinoma; TNL, thin loop of Henle; TKL, thick loop of Henle. Magnification: × 40. The scale bar represents 50 μm.
