Table 1 LD50s for HQBA toward cancer cell lines treated for 3 or 7 days
Cell line | LD50s for HQBA (n M) | ||
|---|---|---|---|
Tissue of origin | 3-Day assay | 7-Day assay | |
MCF7 | Breast cancer | Not effective | 420±160 |
MDA-MB 231 | Breast cancer | 17 400±6900 | 370±130 |
SK-BR3 | Breast cancer | 27 000±9000 | 97±35 |
SUM159 | Breast cancer | 27 000±10 000 | 340±120 |
4T1 | Breast cancer (mouse) | 17±3 | 48±13 |
HeLa | Cervical cancer | 420±170 | 570±160 |
DLD1 | Colorectal cancer | 100±55 | 98±71 |
HCT116 | Colorectal cancer | 1100±800 | 340±160 |
RKO | Colorectal cancer | 1200±720 | 390±220 |
HT29 | Colorectal cancer | 3700±1500 | 1700±500 |
SW480 | Colorectal cancer | 27 000±14 000 | 340±150 |
Rat2 | Fibroblast-rat embryo | 340±88 | 300±250 |
AGS | Gastric cancer | 70±28 | 50±12 |
HUH7 | Hepatocellular carcinoma | 38 000±60 000 | 470±460 |
A204 | Rhabdomyosarcoma | Not effective | 140±70 |
SJSA-1 | Osteosarcoma | Not effective | Not effective |
TC-71 | Ewing's sarcoma | 49±15 | 140±80 |
HT1080 | Fibrosarcoma | 37 000±33 000 | ND |
PA-1 | Teratoma | 190±60 | 50±14 |
hMEC 1 | hMEC (tert) | 42 000±17 000 | 3 300±1900 |
hMEC 2 | hMEC (tert RAS ER) | 43 000±29 000 | 4000±1600 |
hMEC 3 | hMEC (tert RAS ER ΔP53) | 43 000±28 000 | 4000±1600 |
GMO1915C | Primary fibroblast | Not effective | Not effective |
MMEC | Primary mouse mammary epithelial cells | 2500±1100 | 3100±1300 |
