Table 1 For each of the five gene groups (i. to iv.), the table shows the percentage of TSSs located within a CpG island and the percentage of promoters containing a CACGTG motif within ±1 kb of the TSS

From: Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts

Group

Promoters

Total

CpG islands

CACGTG

   

%

P-value

%

P-value

i.

MDSR, Myc-bound

234

86.8

0

62.4

0

ii.

High-affinity non-MDSR promoters (RMA35,5)

718

87.0

0

59.1

0

iii.

Low-affinity non-MDSR promoters (15<RMA<35,5)

3355

83.5

0

41.3

0

iv.

Myc peak below threshold (OCR-RMA 15)

4803

76.4

0

29.0

0.852

v.

No peak

10 672

23.4

1

22.3

1

  1. Abbreviation: TSS, transcription start site.
  2. The enrichment P-value for CpG islands was calculated by using binomial distribution assuming a frequency of TSS located in a CpG island of 0.473 (9731/20 570). The enrichment P-value for the CACGTG motif was calculated by using binomial distribution assuming a frequency of CACGTG motif within 1 kb of a TSS of 0.283325 (5828/20 570).