Figure 5
From: Breaking the ‘harmony’ of TNF-α signaling for cancer treatment
Signaling through TNFR2/p75 is required for proper activation of p38 MAPK in EPCs. (a, c, e) Representative images of phospho-p38 (P-p38) and total-p38 (T-p38) western blot analysis in WT and p75KO EPCs and unaltered LLCs. (b, d, f) Quantification p38 protein level and phosphorylation using densitometric analysis of P-p38 band intensity after adjusting for actin (not shown) and T-p38 band intensity. Band intensity at time 0 for each cell type was set at 100% and percent change over 60 min was calculated. Results represent data from three independent experiments. Statistical significance was assigned when P<0.05.
