Figure 5 | Oncogene

Figure 5

From: Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer

Figure 5

IL-6 and PAI-1 are highly co-expressed in EOC samples. (a) Immunohistochemistry for EGFR, IL-6 and PAI-1 in a primary formalin-fixed, paraffin-embedded EOC sample (characteristics reported in Supplementary Table 1). Representative images from sample no. 22 are shown. (b) IL-6, PAI-1 and IL-8 quantification by ELISA in 23 ascites samples from the same EOC patients. (c) Correlation between IL-6 and PAI-1 levels measured in ascites. The linear regression line, Spearman correlations and P-values are shown.

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