Figure 6 | Oncogene

Figure 6

From: Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer

Figure 6

Expression of EGFR-associated molecules in EOC data set I. (a) Correlation among IL-6, PAI-1 and IL-8 were determined and the values are plotted on a log2 scale. Pearson correlations (r), linear regression and P‐values are reported. (b) Association between IL-6/PAI-1 expression intensities and tumor stage was analyzed on samples filtered for expression higher or lower than the respective median. Asterisk indicates a significant difference by Fisher's exact test. (c) Kaplan–Meier curves reporting the progression-free survival analysis on patient subgroups selected for IL-6/PAI-1 expression higher than the 3rd quartiles and lower than the 1st quartile (log-rank test).

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