Figure 3
From: CpG island shore methylation regulates caveolin-1 expression in breast cancer
Differential Cav1 CGI shore methylation in antiestrogen-resistant breast cancer cell lines. (a) The box-and-whisker plot displays pyrosequencing results of five cell lines. The methylation level is indicated as percentage: 0, no methylation; 100, 100% methylation of the CpG sites. The statistical analysis was performed for MCF7 vs all other cell lines. **P<0.01. For methylation of 3′-CGI shore, all the cell lines were different from each other (P<0.01), except for MCF7-T vs BT474. (b) The box-and-whisker plot displays pyrosequencing results of MCF7-T cells after treating with 5 μM 5-aza-CdR for 6 days. **P<0.01.
