Figure 2

Distribution of truncating APC mutations according to the number and types of somatic hits: cases with one hit (1 mutation/LOH−) are shown in blue, with two hits (1 mutation/LOH+ and 2 mutations/LOH−) in red, and with three hits (2 mutations/LOH+ and 3 mutations/LOH−) in green. The y axis shows case number. Regions with few truncating mutations are highlighted.