Figure 6 | Oncogene

Figure 6

From: Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis

Figure 6

Frequency of APC genotypes in proximal and distal CRCs with two hits to APC. Black asterisk: >5% of proximal cancers. Grey asterisk: >5% of distal cancers. x20AAR, number of intact 20 amino-acid repeats; ARM+, intact armadillo-repeat domain; ARM−, disrupted armadillo-repeat domain; CN, copy-neutral LOH; Del, deletion LOH.

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