Figure 1 | Oncogene

Figure 1

From: Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro

Figure 1

Effect of clec14a-CTLD in cell migration. (a) Schematic representation of GFP, clec14a-GFP and clec14aΔCTLD-GFP. (b) Lysates of COS-7 cells transfected with GFP, clec14a-GFP or clec14aΔCTLD-GFP were analyzed by immunoblotting with anti-GFP or anti-β-actin antibodies. (c) Migration of COS-7 cells transfected with GFP, clec14a-GFP or clec14aΔCTLD-GFP in the wound healing assay was monitored under a light microscope. Images were captured at 0 h (top) and 20 h (bottom). (d) Distance migrated is expressed as percent of control migration. Values represent mean±s.d. of triplicate measurements from one of three independent experiments.

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