Figure 4 | Oncogene

Figure 4

From: Signaling mediated by the NF-κB sub-units NF-κB1, NF-κB2 and c-Rel differentially regulate Helicobacter felis-induced gastric carcinogenesis in C57BL/6 mice

Figure 4

(a–c) Relative mRNA abundance of Th1 cytokines ((a) TNF-α; (b) IL-1β; (c) IFN-γ): gastric corpus, 12-week-old mice infected with H. felis *P<0.05, **P<0.01. (d) Western blot demonstrating expression of NF-κB2 in gastric corpus of WT, Nfkb1−/−, Nfkb2−/− and c-Rel−/− mice infected with H. felis for 6 weeks. (e) DNA-binding enzyme-linked immunosorbent assay (ELISA) demonstrating relative DNA binding of NF-κB2 p52 in gastric mucosa of WT, Nfkb1−/−, Nfkb2−/− and c-Rel−/− mice infected with H. felis for 6 weeks, *P<0.05.

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