Figure 2 | Oncogene

Figure 2

From: NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial–mesenchymal transition

Figure 2

NKX6.1 suppresses the transformation and invasive ability of cancer cells in an inducible expression system. (a) Dox (1 ng/μl)-inducible NKX6.1 expression was established in HeLa cells (HeLa-TR) and was assessed by western blot analysis. β-Actin was used as an internal control. (b–d) Cell proliferation (MTS) (b), colony formation (c) and invasion (d) were performed using HeLa-TR and HeLa-TR-NKX6.1 cells. The results are presented as the mean±s.e. from three independent experiments in triplicates (analyzed by unpaired two-tailed t-test). *P<0.05, **P<0.01 and ***P<0.001.

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