Figure 2 | Oncogene

Figure 2

From: The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain

Figure 2

(a) DCC Map for the p53 tetramer. Four squares delimit the intra-DBD interactions in monomers M1–M4. High correlated motions between couples of TET are highlighted by ellipses A. High anticorrelated motions between TET-DBD couples are highlighted by rectangles B. (b) 2D projection of the concatenated DBD trajectory on the essential subspace along eigenvectors 1 and 2. The structural basin visited by the different monomers is highlighted in different colours (M1–M4 colours as in Figures 1a–d).

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