Figure 3

MLV integration sites within Stat5a. The sequence represents the whole sequence of AF049104 from (5′-)1061th–1207th nt (-3′) (Stat5a gene sequence in GenBank, renumbered according to the nucleotide number form the start of the gene, BLAST: https://blast.ncbi.nlm.nih.gov). The colored letters in blue and red represent the pair of palindromic sequences in the above sequence of which stem of the hairpin structure that is anticipated by m-fold analysis. dG, dH and dS represent Gibbs free energy, enthalpy, and entropy change (kcal/mol) in folding. [Na+]=1.0 mM. Folding temperature is equal to 37°C. The most frequent site (N0.1130, shown by a red arrow) that is shared by different pre-B-cell tumor is shown.⁴¹