Figure 5
From: RNA-binding motif protein 47 inhibits Nrf2 activity to suppress tumor growth in lung adenocarcinoma
RBM47 suppresses tumor progression in vivo. (a) Photographs of the representative tumors xenografted with A549-Luc-shCT cells and A549-Luc-shRBM47#1 cells. Cells were implanted subcutaneously into nude mice, and 24 days later, the tumor volume was measured. (b) Tumor volumes shown on a dot plot chart. n=9 for each condition. (c) Examples of the time-course change in luminescence from xenografted mice. A549-Luc-shCT cells and A549-Luc-shRBM47#1 cells were injected into the tail vein of nude mice. The lung metastasis was monitored by photon counting after intraperitoneal administration of D-luciferin. (d) Photon counts shown by a dot plot chart. n=6 for shCT and n=10 for shRBM47#1. The horizontal lines in the dot plots indicate average values in (b) and (d). ph/s: photon counts/second.
