Figure 6 | Oncogene

Figure 6

From: Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality

Figure 6

NRP1 expression predicts metastasis and PCSM following RP. (a) NRP1 expression in Mayo Clinic patient samples. Each sample is annotated in the colored matrix below the plot. ADT, androgen deprivation therapy; ECE, extra-capsular extension; LNI, lymph node invasion; MET, metastasis; RT, radiation therapy; SM, surgical margin; SVI, seminal vesicle invasion. (b) NRP1 expression in patients positive and negative for METS. (c) ROC curve for NRP1 expression predicting metastasis. (d) NRP1 expression in patients positive and negative for PCSM. (e) ROC curve for NRP1 expression predicting PCSM.

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