Figure 7 | Oncogene

Figure 7

From: Neuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality

Figure 7

High NRP1 expression in RP samples is prognostic of metastatic progression and cancer-specific mortality in a natural history cohort. Waterfall plots showing NRP1 expression in JHMI patient cohorts in (a) post-RP and (b) post-BCR samples. Each sample is annotated in the colored matrix below the plot. ECE, extra-capsular extension; LNI, lymph node invasion; MET, metastasis; SM, surgical margin; SVI, seminal vesicle invasion. Boxplots showing NRP1 expression in patients positive and negative for METS (a) and PCSM (b). Kaplan–Meier curves showing MET-free (a) and PCSM-free (b) survival for NRP1 high and low expression groups.

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