Figure 6
From: Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells
Cre-LoxP technologies reveal multiple cellular origin for MBG3. Schematic representation of the cells of origin of MBG3 and CPCs. Whereas all cerebellar neural progenitors tested are transformed into MBG3 by Myc overexpression and Trp53 loss of function, cells committed to the CP formed CPCs.
