Table 1 Whole-genome bisulfite sequencing of 22 human samples
From: A DNA methylation map of human cancer at single base-pair resolution
Sample ID | Status | Tissue | Origin | Total reads | Coverage (fold) | AVR Meth. | # HMRs | Coverage (bp) | Coverage (%) | Average size (bp) |
|---|---|---|---|---|---|---|---|---|---|---|
CD19 | Normal | B cells | Primary | 318 714 023 | 6 | 76 | 56 894 | 56 552 703 | 1.9 | 655 |
Brain_G | Normal | Brain (gray matter) | Primary | 275 099 021 | 5.7 | 74.9 | 46 693 | 54 771 999 | 1.8 | 783 |
Brain_W | Normal | Brain (white matter) | Primary | 557 237 398 | 11.1 | 77.1 | 58 215 | 67 842 262 | 2.2 | 809 |
Breast | Normal | Breast | Primary | 606 872 747 | 15.1 | 73 | 63 648 | 77 291 411 | 2.5 | 871 |
Colon | Normal | Colon | Primary | 609 043 678 | 13.7 | 69.6 | 45 020 | 58 103 004 | 1.9 | 925 |
Liver | Normal | Liver | Primary | 1 003 013 615 | 25.2 | 73.2 | 54 545 | 75 779 635 | 2.5 | 957 |
Lung | Normal | Lung | Primary | 333 333 332 | 7.2 | 74.4 | 43 259 | 48 772 726 | 1.6 | 748 |
Placenta | Normal | Placenta | Primary | 447 848 405 | 10.4 | 58.2 | 76 898 | 586 617 157 | 19.3 | 4942 |
Prostate | Normal | Prostate | Primary | 702 575 404 | 17.3 | 74.5 | 66 711 | 81 099 795 | 2.7 | 899 |
Colon_P | Cancer | Colorectal cancer | Primary | 670 281 443 | 16.7 | 66.5 | 71 774 | 181 767 349 | 6.0 | 1902 |
Colon_M | Cancer | Colorectal cancer metastasis | Primary | 652 566 967 | 16.3 | 62.4 | 86 810 | 330 654 110 | 10.9 | 2825 |
Liver_P1 | Cancer | Liver carcinoma | Primary | 658 876 767 | 16.2 | 50.6 | 72 633 | 558 373 155 | 18.4 | 4919 |
Liver_P2 | Cancer | Liver carcinoma | Primary | 718 665 563 | 17.5 | 64.6 | 43 965 | 124 483 271 | 4.1 | 1274 |
468PT | Cancer | Breast cancer | Cell line | 626 288 553 | 15.4 | 57.1 | 186 645 | 873 241 247 | 28.8 | 2710 |
468LN | Cancer | Breast cancer metastasis | Cell line | 600 134 926 | 14.3 | 42.8 | 192 305 | 1 081 026 523 | 35.6 | 3646 |
U87MG | Cancer | Glioma | Cell line | 281 524 883 | 6.3 | 55.7 | 78 444 | 660 392 120 | 21.7 | 4682 |
SH5YSY | Cancer | Neuroblastoma | Cell line | 277 166 468 | 6.2 | 65.4 | 85 756 | 586 978 640 | 19.3 | 3614 |
PC3 | Cancer | Prostate cancer | Cell line | 697 835 354 | 17.8 | 54.2 | 141 730 | 779 429 448 | 25.7 | 2826 |
22RV1 | Cancer | Prostate cancer | Cell line | 465 560 242 | 11.4 | 55.2 | 102 806 | 701 717 497 | 23.1 | 3715 |
H1437 | Cancer | Lung adenocarcinoma | Cell line | 333 333 332 | 7.9 | 48.1 | 106 188 | 1 059 922 017 | 34.9 | 6484 |
H1672 | Cancer | Small cell lung cancer | Cell line | 329 691 560 | 7.4 | 65.6 | 87 979 | 513 193 022 | 16.9 | 3016 |
H157 | Cancer | Squamous cell cancer | Cell line | 333 333 332 | 7.8 | 41.8 | 107 206 | 1 159 333 666 | 38.2 | 6942 |
