Figure 4 | Oncogene

Figure 4

From: Differential expression of miR16 in glioblastoma and glioblastoma stem cells: their correlation with proliferation, differentiation, metastasis and prognosis

Figure 4

Effects of miR16 on GBM proliferation and apoptosis. (a) Changes of proliferation potential in GBM cell lines SGH44, U87, U251 and their stem cell counterparts after administration of miR16 mimic and inhibitor were evaluated by CCK8 assay. Comparison of the difference of proliferation potential at different time point between groups of miR16 mimic and miR16 inhibitor or NC was performed. (b) The cell cycle distribution in glioblastoma cell lines and their stem cell counterparts were examined using flow cytometry assay. (c) Apoptotic rate of glioblastoma cells and their stem cell counterparts was estimated by flow cytometry analysis. Comparison of the difference of apoptotic rate between groups of miR16 mimic and miR16 inhibitor or NC was also performed.

Back to article page