Figure 7 | Oncogene

Figure 7

From: Differential expression of miR16 in glioblastoma and glioblastoma stem cells: their correlation with proliferation, differentiation, metastasis and prognosis

Figure 7

miR16 inhibitor promoted the tumor growth in vivo. Nude mice received intracerebral transplantation of U251 or U251-GSCs transfected with miR16 mimic, inhibitor or scrambled control. (a) Comparison of tumor size between groups of miR16 inhibitor, miR16 mimic group and scrambled control; (b) Expression level of miR16 and its target genes, including Bcl2, CDK6, CCND1, CCNE1, SOX5 and Ki67 in tumor xenograft tissues were examined by qRT-PCR and immunohistochemistry. Green block were low expression areas.

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