Figure 4

Enrichment and correlation of CysDep and TNFα gene signatures in breast tumors and cancer cell lines. (a) The activities of CysDep gene signature in a data set of breast cancer cell lines in relation to ER status. (b) The correlation of CysDep and TNFα gene signatures in a panel of breast cancer cell lines. (c, d) The activities of CysDep gene signature in a data set of breast cancer relative to ER status (c) or intrinsic subtypes (d). (e) The correlations of CysDep and TNFα gene signature in a panel of breast tumor data sets. (f) Kaplan-Meyer survival curves of high and low CysDep-Sig breast tumors.32