Table 1 Selected CAIX-BirA*FLAG high-confidence proximal associating proteins identified by BioID in MDA-MB-231 cells

From: The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion

Functional class

Gene symbol

Full name

Description

Controls

Pool A

Pool B

SAINT score

Transporters

SLC3A2

Solute carrier family 3 member 2

Amino acid transport heavy chain subunit CD98hc

37

35

116

115

1.00

 

SLC38A2

Solute carrier family 38 member 2

Glutamine transporter SNAT2

12

12

56

61

1.00

 

SLC4A7

Solute carrier family 4 member 7

Sodium bicarbonate transporter NBC2/3

5

4

52

28

1.00

 

SLC27A4

Solute carrier family 27 member 4

Fatty acid transporter FATP4

6

5

18

23

0.99

Cell adhesion

ITGB1

Integrin subunit β1

 

11

9

66

45

1.00

 

ITGA6

Integrin subunit α6

 

7

5

54

48

1.00

 

ITGA2

Integrin subunit α2

   

51

47

1.00

 

ITGA3

Integrin subunit α3

 

4

 

46

24

1.00

 

ITGA5

Integrin subunit α5

   

9

6

1.00

Matrix remodeling

MMP14

Matrix metallopeptidase 14

 

5

3

18

31

1.00

  1. For each associating protein, the ‘controls’ column shows the top two spectral counts detected between the 20 control runs. Pool A and B columns display the peptide counts detected in each of the biological replicates, and their corresponding SAINT score is shown in the adjacent column.