Figure 3
The 13 lung cancer specific MST loci and 8 MST loci specific for other diseases can differentiate between the lung cancer and non-cancer control sample groups. The blue and red bars represent the non-cancer control and lung cancer samples, respectively. (a) A sample with 61% or more of the 13 MST loci with cancer genotype will be termed ‘at-risk’ for lung cancer with sensitivity and specificity values of 0.90 and 0.94. (b) A sample with 57% or more of the 21 MST loci with cancer genotype will be termed ‘at-risk’ for lung cancer with sensitivity and specificity values of 0.93 and 0.97. The vertical black line corresponds to the optimum cutoff values found from the ROC analysis.
