Figure 5
From: SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer
Stromal SerpinB2 attenuates PDAC local invasion in mixed cell allografts. Photomicrographs and quantification of local cell invasion into muscle tissue (a, b) or subcutaneous fat (c, d), by either wild-type or SerpinB2−/− MEF:PDAC tumours. Individual values shown are from five or four animals per group in WT or SerpinB2−/− respectively, with mean±s.e.m. denoted. Statistical analyses were performed using unpaired t-tests. (e) uPA enzymatic activity (IU/mg) from either wild-type or SerpinB2−/− MEF:PDAC tumour lysates (bars represent mean±s.e.m., n=3).
