Figure 6

Selected clinical specimens illustrate ERBB2-amplified breast cancer as a heterogenous disease. Immunohistochemical detection of ERBB2 (left column) and EGFR (right column), magnification × 200. EGFR-high/ERBB2-positive breast cancer (a and b) and ERBB2-amplified breast cancer without positive staining of EGFR (c).