Table 2 Impact of erlotinib (E) and combinatorial treatments (ET, EP, TP, TPE) on long-term signaling in SKBR3 cells and HCC1954 cells (Figure 4)
Cell line | SKBR3 | HCC1954 | ||||||
|---|---|---|---|---|---|---|---|---|
pRPS6 | pRB | pRPS6 | pRB | |||||
Hours | 12 | 24 | 12 | 24 | 12 | 24 | 12 | 24 |
Control | 64.6 | 28.6 | 87.0 | 93.7 | 43.8 | 12.6 | 59.9 | 42.2 |
E | 19.5 | 13.0 | 46.9 | 46.6 | 12.4 | 0.7 | 36.4 | 10.6 |
ET | 3.1 | 0 | 50.4 | 14.3 | 8.5 | 0.4 | 37.3 | 8.6 |
EP | 53.4 | 10.4 | 70.0 | 26.8 | 14.1 | 0 | 37.1 | 4.4 |
TP | 59.0 | 5.7 | 78.2 | 77.7 | 96.5 | 20.5 | 100.0 | 65.3 |
TPE | 12.5 | 0.1 | 74.7 | 57.6 | 21.2 | 3.9 | 51.2 | 18.2 |
