Table 2 Number of genes upregulated and downregulated following in vitro studies where a mutant form of p53 is overexpressed
From: More targets, more pathways and more clues for mutant p53
Number of genes | % Of the total number of genes | Number of mutations on different p53 codons, leading to upregulation | Number of mutations on different p53 codons, leading to downregulation |
|---|---|---|---|
151 | 8.2% | 0 | 1 |
698 | 37.8% | 1 | 0 |
446 | 24.2% | 0 | >1 |
503 | 27.2% | >1 | 0 |
401 | 22% | 0 | ⩾3 |
260 | 14% | ⩾3 | 0 |
Inconsistent | |||
 48 | 2.6% | ⩾1 | ⩾1 |
