Figure 4
From: Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions

Epigenetic and genetic variations at the three loci investigated in our 50 adenomas. For each locus, the upper row of squares shows the methylation status of each tumor (black, hypermethylation; gray, normal methylation; white, hypomethylation), and the lower row indicates the CNA status (A, amplification; D, deletion; red, loss of the active (unmethylated) allele; green, gain in the number of active (unmethylated) alleles; white, no CNA).