Table 2 Characteristics of the 50 patients with precancerous colorectal lesions included in the study

From: Epigenetic silencing of monoallelically methylated miRNA loci in precancerous colorectal lesions

Patient no.

Sex

Age

Colon segment involved a

Maximum lesion diameter (mm)

Macroscopic appearance b

Pit pattern c

Microscopic appearance

Dysplasia d

No. of lesions present e

1

F

75

Tra

20

IIa

IIIS-IIIL

VA

High

7

2

F

75

Tra

40

IIa-IIc

IIIS-IIIL

TA

High

1

3

F

54

Cec

45

IIa

IIIL

TVA

Low

16

4

M

73

Asc

30

Is

nr

TVA

High

1

5

F

69

Asc

45

Ip

nr

TVA

high

1

6

M

74

Rec

40

Is

IV

VA

high

2

7

M

80

Asc

40

IIa

IIIL

TVA

Low

1

8

M

77

Cec

25

IIa

IIIL

VA

Low

1

9

M

71

Sig

30

IIa

IIIL

TVA

Low

2

10

M

89

Rec

30

Is

IV

TA

Low

3

11

F

85

Sig

25

Is-IIa

IV

TA

Low

1

12

F

63

Sig

35

Ip

IV

VA

Low

1

13

M

82

Asc

15

IIa

IIIL

VA

Low

2

14

F

73

Asc

25

IIa-IIc

IIIs-IIIL

TA

Low

1

15

F

70

Cec

25

IIa

IIIL

TVA

Low

2

16

M

70

Asc

15

Is

IV

TVA

Low

7

17

M

63

Asc

45

Is

IIIL-IV

TVA

Low

1

18

F

73

Sig

20

Ip

IV

TVA

Low

1

19

M

60

Des

30

Is

IV-Vi

TVA

High

1

20

M

68

Asc

30

Is-IIa

IIIL-IV

TVA

High

1

21

M

55

Cec

25

Is-IIa

IIIL-IV

SSA

Low

1

22

M

64

Sig

12

Ip

IIIL

TA

Low

1

23

M

78

Asc

50

Is

IV-Vi

TA

Low

1

24

F

69

Rec

90

Is-IIa

IV

TVA

Low

1

25

F

78

Rec

60

Is-IIa

IV

TVA

Low

1

26

M

72

Asc

30

Is

IV

TVA

High

2

27

M

76

Sig

30

Is

IV-Vi

TA

High

1

28

M

75

Rec

25

Is

IV-Vn

TVA

High

6

29

M

66

Asc

30

IIa

IIIL

TA

High

2

30

F

66

Asc

30

Is-IIa

IV

TA

High

2

31

M

75

Tra

18

IIa

IIIL

TA

Low

1

32

M

61

Asc

40

Is-IIa

IV

TVA

Low

20

33

M

84

Cec

30

Is

Vn

TVA

High

1

34

M

59

Tra

30

IIa-IIc

IIIs-IIIL

TA

Low

1

35

F

73

Rec

50

Is

IV

VA

Low

1

36

F

73

Des

25

Is

IV

TA

Low

1

37

M

59

Rec

60

Is

IV-Vi

TVA

High

1

38

M

75

Asc

40

IIa

II

TA

Low

6

39

M

75

Asc

50

Is

Vn

TVA

High

7

40

M

77

Sig

25

IIa-IIc

IIIs-IIIL

TA

Low

1

41

F

72

Asc

20

Is

IV

TVA

Low

1

42

F

66

Sig

35

Ip

IV

TA

Low

1

43

F

78

Rec

45

Ip

IV

TVA

High

1

44

M

74

Sig

25

Ip

IIIs-IV

TA

Low

1

45

M

60

Cec

30

Is

IV

TVA

Low

2

46

M

62

Des

22

Ip

nr

TA

Low

1

47

F

68

Asc

16

IIa

nr

TA

High

1

48

F

46

Des

30

Ip

nr

TVA

High

2

49

M

75

Cec

20

Is

nr

TVA

Low

1

50

M

59

Sig

8

Ip

nr

TA

Low

2

  1. aAbbreviations: Asc, ascending colon; Cec, cecum; Des, descending colon; nr, pit pattern not reported by the endoscopist; Rec, rectum; Sig, sigma; SSA, sessile serrated adenoma; TA, tubular adenoma; Tra, transversum; TVA, tubulovillous adenoma; VA, villous adenoma.
  2. bClassified according to the Paris Endoscopic Classification of Superficial Neoplastic Lesions.60
  3. cKudo classification of colonic crypt morphology.61
  4. dHighest degree of dysplasia in the lesion based on the WHO classification of tumors of the digestive system.62
  5. eTotal number of lesions noted during the study colonoscopy, including those used in the present study.