Figure 3 | Oncogenesis

Figure 3

From: A novel orthotopic mouse model of head and neck cancer and lymph node metastasis

Figure 3

Western blotting and IHC of the USC-HN3-GFP, USC-HN3-GFP-G1 and USC-HN3-GFP-G2 cell lines. (a) Western blot demonstrating progressively increasing expression of OCT-4, ALDH1A3, CAV-1, TLR-4, TRIM-29 and MMP-7 in the metastatic USC-HN3-GFP-G1 and USC-HN3-GFP-G2 cell lines. E-cadherin expression is progressively decreasing in the metastatic USC-HN3-GFP-G1 and USC-HN3-GFP-G2 cell lines as compared with the USC-HN3-GFP cell line. (b) Immunocytochemistry ( × 20) of USC-HN3-GFP, USC-HN3-GFP-G1 and USC-HN3-GFP-G2 cell lines demonstrating increasing expression of ALDH1A3, TRIM-29, MMP-7 and OCT-4. E-cadherin expression is progressively decreasing in the metastatic USC-HN3-GFP-G1 and USC-HN3-GFP-G2 cell lines.

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