Figure 5
From: A novel orthotopic mouse model of head and neck cancer and lymph node metastasis
Western blotting and IHC analysis of advanced stage patient HNSCC samples. (a) Western blotting demonstrating overexpression of OCT-4, ALDH1A3 and TRIM-29 in the patient tumor (T) and LN as compared with normal (N) tissue. (b, c) IHC analysis of an advanced stage HNSCC sample of a patient demonstrating increasing expression of TRIM-29, ALDH1A3 and CAV-1 in the tumor and LNs as compared with normal tissue. (d) IHC analysis of an advanced stage HNSCC sample of a patient demonstrating increasing expression of MMP-7 and β-catenin in the tumor as compared with normal tissue.
