Table 3 Associations between CIMP status and other molecular features
From: Epigenetic and genetic features of 24 colon cancer cell lines
Feature | Issa 16 panel 1 | Weisenberger et al. 20 panel 2 | ||||
|---|---|---|---|---|---|---|
CIMP+ (%) | CIMP− (%) | P-value | CIMP+ (%) | CIMP− (%) | P-value | |
MSI | 6 (75) | 2 (25) | 0.09 | 5 (62) | 3 (38) | 0.03 |
BRAF mut | 3 (75) | 1 (25) | 0.29 | 3 (75) | 1 (25) | 0.07 |
KRAS mut | 6 (43) | 8 (57) | 0.38 | 3 (21) | 11 (79) | 0.18 |
PIK3CA mut | 4 (44) | 5 (55) | 0.67 | 5 (56) | 4 (44) | 0.06 |
PTEN mut | 2 (100) | 0 (0) | 0.99 | 1 (50) | 1 (50) | 0.57 |
TP53 mut | 7 (47) | 8 (53) | 0.65 | 2 (13) | 13 (87) | 0.01 |
