Figure 3 | Oncogenesis

Figure 3

From: Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer

Figure 3

Survival of patients stratified by the 8-gene score in the METABRIC data set. The overall survival of patients in the METABRIC data set was analyzed according to the 8-gene score in selected settings in all patients (a) or in ER-positive patients only (b). (a) TP53 mutation was compared in high vs low 8-gene score (split by the median). The expression of the proliferation marker Ki67 was divided by dichotomy across the median, and patients in each of these groups were then stratified according to their 8-gene score (split by quartiles). Disease stages (Stage I—Stage III) were stratified by the median 8-gene score. (b) ER+ Grade 3, ER+ lymph node-negative (LN−) and ER+ LN+ tumors were stratified by the quartiles.

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