Figure 7 | Oncogenesis

Figure 7

From: DNA damage signaling guards against perturbation of cyclin D1 expression triggered by low-dose long-term fractionated radiation

Figure 7

Apoptosis in ATM- and NBS1-deficient cells following FR. (a) Annexin V staining was performed for untreated control cells and cells treated with FR for 21 days. Asterisks indicate a significant increase in annexin V-positive cells compared with control cells. (b) Treatment with KU55933 induced apoptosis in ATM-complemented cells exposed to FR for 31 days. Cells were treated with KU55933 for 48 h. Asterisks indicate a significant increase in annexin V-positive cells compared with cells without KU55933 treatment.

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