Table 2 APRIL serum levels associate to features of advanced disease in colorectal cancer patients

From: Circulating APRIL levels are correlated with advanced disease and prognosis in rectal cancer patients

Factor

Case number

APRIL serum levels

P-value

  

Low

High

 

Overall

432

   

Gender

   

0.805

 Male

237

128

109

 

 Female

195

103

92

 

Age

   

0.349

 <67

206

115

91

 

 ⩾67

226

116

110

 

Organ

    

 Colon

221

106

115

0.015

 Rectum

209

125

84

 

 Both

2

0

2

 

Stage

   

0.013

 I

117

71

46

 

 II

106

60

46

 

 III

106

54

52

 

 IV

95

39

56

 

 Unknown

8

7

1

 

Grade

    

 G1

16

7

9

0.224

 G2

328

179

147

 

 G3

76

35

41

 

 Unknown

12

10

4

 

Lymphatic metastasis

   

0.004

 Negative

224

132

92

 

 Positive

203

94

109

 

 Unknown

5

5

0

 

Distant metastasis

   

0.005

 Negative

329

185

144

 

 Positive

95

39

56

 

 Unknown

8

7

1

 
  1. APRIL serum levels and clinicopathological parameters APRIL levels were divided into high and low using the mean value as a cutoff. APRIL levels were not associated with parameters such as gender, age and grade (data not shown), whereas APRIL levels differ significantly for stage, lymphatic and distant metastasis (all χ2 test, except χ2 test by trend was performed for analysis of stage).
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