Table 3 Correlation between APRIL serum levels and clinicopathological parameters of rectal cancer patients

From: Circulating APRIL levels are correlated with advanced disease and prognosis in rectal cancer patients

Factor

APRIL serum levels

P-value

 

Low

High

 

Overall (n=209)

   

Gender

   

 Male

70

45

0.729

 Female

55

39

 

Age

  

0.901

 <67

74

49

 

67

51

35

 

Stage

  

0.016

 I

46

22

 

 II

22

13

 

 III

36

21

 

 IV

16

27

 

 Unknown

5

1

 

Grade

  

0.792

 G1

4

2

 

 G2

92

63

 

 G3

21

16

 

 Unknown

8

3

 

Lymphatic metastasis

  

0.031

 Negative

68

35

 

 Positive

53

49

 

 Unknown

4

0

 

Distant metastasis

  

0.002

 Negative

104

56

 

 Positive

16

27

 

 Unknown

   
  1. APRIL levels were divided into high and low using the median value as a cutoff. APRIL levels correlate significantly with stage, lymphatic and distant metastasis (χ2 test, χ2 test by trend was performed for analysis of stage).