Figure 1 | Oncogenesis

Figure 1

From: Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes

Figure 1

MIBC exosomes increase expression of mesenchymal markers in urothelial cells. (a) qRT–PCR for mesenchymal genes expressed in urothelial cells treated with PBS, human embryonic kidney (HEK) exosomes or MIBC exosomes for 4 or 6 h. qRT–PCR was repeated at least three times for each gene. (b) Confocal microscopy images of α-SMA expression in urothelial cells treated with PBS or MIBC exosomes for 24 h. Confocal microscopy was performed at least three times. A representative image is shown. Scale bar=20 μm. DAPI, 4,6-diamidino-2-phenylindole.

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