Table 2B Cross-tables of expression of HER1/ERBB1 and HER2/ERBB2
From: Uncoupling of EGFR–RAS signaling and nuclear localization of YBX1 in colorectal cancer
Parameter | HER1 positive (%) | HER1 negative (%) | P-value | HER2 positive (%) | HER2 negative (%) | P-value |
|---|---|---|---|---|---|---|
All cases | 306 (72) | 107 (25) | 336 (79) | 87 (21) | ||
Age | ||||||
>72 | 175 (74) | 63 (26) | 0.528 | 184 (77) | 54 (23) | 0.221 |
<72 | 141 (76) | 44 (24) | 152 (82) | 33 (18) | ||
Gender | ||||||
Male | 182 (77) | 53 (23) | 0.147 | 191 (81) | 44 (19) | 0.294 |
Female | 134 (71) | 54 (29) | 145 (77) | 43 (23) | ||
pT status | ||||||
pT1/pT2 | 72 (73) | 26 (27) | 0.7 | 75 (77) | 23 (23) | 0.394 |
pT3/pT4 | 236 (75) | 77 (25) | 252 (81) | 61 (19) | ||
Nodal status | ||||||
N0 | 164 (77) | 50 (23) | 0.355 | 170 (79) | 44 (21) | 0.997 |
N1 | 152 (73) | 57 (27) | 166 (79) | 43 (21) | ||
Metastasis | ||||||
M0 | 278 (75) | 91 (25) | 0.433 | 294 (80) | 75 (20) | 0.747 |
M1 | 38 (70) | 16 (30) | 42 (78) | 12 (22) | ||
Grade | ||||||
G1 | 3 (75) | 1 (25) | 0.974 | 4 (100) | 0 (0) | 0.305 |
G2/G3 | 306 (74) | 106 (26) | 326 (79) | 86 (21) | ||
R status | ||||||
R0 | 280 (74) | 97 (26) | 0.429 | 301 (80) | 76 (20) | 0.771 |
R1 | 18 (82) | 4 (18) | 17 (77) | 5 (23) | ||
Localization | ||||||
Right colon | 126 (72) | 49 (28) | 0.123 | 127 (73) | 48 (27) | 0.005 |
Left colon | 177 (79) | 48 (21) | 189 (84) | 36 (16) | ||
KRAS status | ||||||
WT | 241 (74) | 86 (26) | 0.079 | 261 (80) | 66 (20) | 0.924 |
MUT | 45 (85) | 6 (15) | 42 (79) | 11 (21) | ||
