Table 2C Cross-tables of c-terminal HER4/ERBB4 and n-terminal HER4/ERBB4
From: Uncoupling of EGFR–RAS signaling and nuclear localization of YBX1 in colorectal cancer
Parameter | HER4c positive | HER4c negative | P-value | HER4n positive | HER4n negative | P-value |
|---|---|---|---|---|---|---|
All cases | 276 (65) | 147 (35) | 196 (46) | 227 (54) | ||
Age | ||||||
>72 | 154 (65) | 84 (35) | 0.79 | 102 (43) | 136 (57) | 0.104 |
<72 | 122 (66) | 63 (34) | 94 (51) | 91 (49) | ||
Gender | ||||||
Male | 149 (63) | 86 (37) | 0.373 | 114 (49) | 121 (51) | 0.316 |
Female | 127 (68) | 61 (32) | 82 (44) | 106 (56) | ||
pT status | ||||||
pT1/pT2 | 62 (63) | 36 (37) | 0.686 | 42 (43) | 56 (57) | 0.511 |
pT3/pT4 | 205 (66) | 108 (34) | 146 (47) | 167 (53) | ||
Nodal status | ||||||
N0 | 140 (65) | 74 (35) | 0.94 | 92 (43) | 122 (57) | 0.163 |
N1 | 136 (65) | 73 (35) | 104 (50) | 105 (50) | ||
Metastasis | ||||||
M0 | 242 (66) | 127 (34) | 0.706 | 165 (45) | 204 (55) | 0.081 |
M1 | 34 (63) | 20 (37) | 31 (57) | 23 (43) | ||
Grade | ||||||
G1 | 3 (75) | 1 (25) | 0.678 | 1 (25) | 3 (75) | 0.383 |
G2/G3 | 268 (65) | 144 (35) | 193 (47) | 219 (53) | ||
R status | ||||||
R0 | 245 (65) | 132 (35) | 0.458 | 174 (46) | 203 (54) | 0.443 |
R1 | 16 (73) | 6 (27) | 12 (55) | 10 (45) | ||
Localization | ||||||
Right colon | 117 (67) | 58 (33) | 0.615 | 85 (49) | 90 (51) | 0.277 |
Left colon | 145 (64) | 80 (36) | 97 (43) | 128 (57) | ||
KRAS status | ||||||
WT | 212 (65) | 115 (35) | 0.479 | 154 (47) | 173 (53) | 0.449 |
MUT | 37 (70) | 16 (30) | 22 (42) | 31 (58) | ||
