Table 2 Gender-specific median ages and distributions of SNP309 genotypes in the unselected cohort of RCC patients

From: Homozygous G/G variant of SNP309 in the human MDM2 gene is associated with earlier tumor onset in Caucasian female renal cell carcinoma patients

RCC patients

All

SNP309

  

T/T

T/G

G/G

Females

 Age in years: median (range)

68 (48–89)

73 (55–84)

68 (48–89)

59.5 (55–83)

Males

 Age in years: median (range)

67 (46–91)

73 (35–91)

66 (39–88)

68.5 (44–81)

  1. Female RCC patients with a G/G SNP309 genotype (median age 59.5 years) were diagnosed 13.5 years earlier than the T/T females (median age 73 years), a difference that was statistically significant.
  2. The significance of different genotype distributions among the patient groups was calculated by the two-sided exact χ2-test using IBM SPSS Statistics 20 software (SPSS-Science, Chicago, IL, USA). P-values <0.05 were regarded as significant.
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