Table 3 Combination therapy with tamoxifen and diazoxide of the DMBA-induced rat mammary carcinoma. (reproduced from ref. 203)
Tamoxifen 5 mg/kg | Tamoxifen 50 mg/kg | |||
|---|---|---|---|---|
Monotherapy | +Diazoxide 200 mg/kg | Monotherapy | +Diazoxide 200 mg/kg | |
Remission (%) | 53 | 47 | 50 | 59 |
Tumor weight compared to controls (%) | 75 | 49 | 31 | 39 |
Duration of remission (weeks) | 7 | 12 | 8.5 | 12 |
