Figure 1 | Oncogenesis

Figure 1

From: Loss of OLFM4 promotes tumor migration through inducing interleukin-8 expression and predicts lymph node metastasis in early gastric cancer

Figure 1

Immunohistochemical staining of the OLFM4 in sections of gastric cancer. (a) Representative tissue microarray of OLFM4 expression in tumor sections and adjacent non-tumor tissues. OLFM4 was highly expressed in tumor sections than non-tumor tissues (P<0.001). Relative OLFM4 expression was calculated as the Log2 value of T-score/N-score. N, matched non-tumor tissue. T, gastric cancer tissue; (b) Representative images of OLFM4 staining in tumor sections from patients with and without LNM. OLFM4 expression score was lower in patients with LNM (mean±s.e.m.: 4.63±0.44) than that in patients without LNM (mean±s.e.m.: 6.52±0.32) (P=0.004). The box plot shows the full range of variation (error bars: min and max) with the line representing median. (c) Representative microphotographs of intratumoral low and high expression of OLFM4 and their regional magnifications; Original magnification: × 200. (d) The percentage of patients with OLFM4 high or low expression according to the differentiation, T stage, LNM and TNM stage in EGC patients.

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