Figure 3 | Oncogenesis

Figure 3

From: Loss of OLFM4 promotes tumor migration through inducing interleukin-8 expression and predicts lymph node metastasis in early gastric cancer

Figure 3

Establishment of models to predict LNM in patients with EGC. (a) ROC analysis for the predictive value of combined size & differentiation with OLFM4 model, size & differentiation model and OLFM4 model in LNM of EGC patients. (b) C-index was examined to compare the predictive accuracies of tumor size, differentiation and OLFM4 expression. (c) Nomogram generation for predicting LNM integrated with tumor size (1 represents<2 cm, 2 represents>2 cm), differentiation (1 represents well and moderate differentiation, 2 represents poor differentiation) and OLFM4 expression (1 represents high expression, 2 represents low expression). (d) Calibration curve for nomogram-predicted and observed probability of LNM. (e) The patients were stratified into low and high-risk groups according to nomogram-predicted score with the cutoff value determined by ROC analysis, and the percentage of patients with or without LNM in each group was demonstrated. P-value<0.05 was considered statistically significant.

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