Table 2 Composition of the 6-GPS

From: Multi-omics landscapes of colorectal cancer subtypes discriminated by an individualized prognostic signature for 5-fluorouracil-based chemotherapy

Signature

ROEs (Ra>Rb)

β

P-value

FDR

C-index

Gene pair 1

CHTOP>CAPN2

1.22

6.37E-05

1.89E-03

0.63

Gene pair 2

MRPL4>AXL

0.98

4.12E-05

1.70E-03

0.60

Gene pair 3

SLC19A1>NREP

1.09

2.19E-03

1.43E-02

0.59

Gene pair 4

PUS1>LTBP2

0.61

8.74E-03

3.39E-02

0.57

Gene pair 5

MCM2>IFRD2

0.66

1.18E-02

3.89E-02

0.57

Gene pair 6

SLC19A1>WWC2

1.20

9.92E-05

2.41E-03

0.56

  1. Note: ROEs represent the relative expression ordering of gene pair (Ra>Rf); β and P-value are the statistics calculated from the univariate Cox regression model. β represents the risk coefficient of the REO for gene pair (a, b), where β>0 indicates that Ra> Rb is a risk factor, otherwise a protective factor; P-value represents the significance of the REO for gene pair (a, b). All the P-values were adjusted using the Benjamini–Hochberg procedure.
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