Figure 8
ARHGEF5 upregulation associated with EMT-related gene expression correlates with poor prognosis in patients with colorectal cancers. The correlation between ARHGEF5 and E-cadherin (CDH1) (a), ARHGEF5 and Snail (SNAI1) (b), and ARHGEF5, CDH1 and SNAI1 (c) expression and prognosis in colorectal cancer patients was estimated using the Kaplan–Meier method42 based on the transcriptome data set from the TCGA project. Statistical significance was calculated using the log-rank test. (d) The correlation between ARHGEF5 expression and the prognosis of pancreatic cancer patients was estimated.
