Figure 3 | Oncogenesis

Figure 3

From: Axl-EGFR receptor tyrosine kinase hetero-interaction provides EGFR with access to pro-invasive signalling in cancer cells

Figure 3

Hetero-interaction of EGFR and Axl RTKs. (a) CoIP of Axl and EGFR followed by western blot probing for presence in the complexes of Axl (left blot) and EGFR (right blot). Control coIP antibody was anti-GAPDH (Ctrl Ig1). (b) Bimolecular fluorescence complementation (BiFC) images showing EGFR-Axl complex formation followed by fluorescence quantitation bar graph and fluorescence intensity over time following EGF addition. Data are mean±s.e.m. (N=3 separate experiments); **P<0.01, *P<0.05 versus untreated.

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