Figure 1 | Oncogenesis

Figure 1

From: Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice

Figure 1

DEN-dependent HCC in Tamoxifen (TAM)-inducible hepatocyte-specific SMAD7 Tg and SMAD7 KO mice. (a) Plasmid constructs used for generating Albumin-SMAD7 Tg and SMAD7fl/fl mice. (b) Experimental design of the DEN-induced HCC in TTR-Cre × SMAD7 Tg or KO mice. (c) Smad7 levels were analyzed by RT–PCR and (d) immunohistochemistry (positive staining is indicated by brown color).

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