Figure 1 | Oncogenesis

Figure 1

From: Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner

Figure 1

LZAP depletion results in downregulation of endogenous wild-type and mutant p53. LZAP and p53 protein (left) or relative to GPDH mRNA levels (right) in U2OS (a), UNC10 (b) or HCT116 (c) cells transfected with control or siRNAs specific to LZAP. mRNA levels were determined using qRT-PCR; mean from two experiments is shown, error bar represents s.d.; P-values were calculated using unpaired t-test.

Back to article page