Table 1 Patient characteristics

From: Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner

Characteristics

Total

LZAP low

LZAP high

P-value

Number of cases

178

81 (45.5%)

97(55.5%)

 

Gender

   

0.88

 Male

86 (48.3%)

38 (46.9%)

48 (49.5%)

 

 Female

91 (51.1%)

42 (51.9%)

49 (50.5%)

 

 NA

1 (0.56%)

0

1 (1.2%)

 

Age at Dx

   

0.34

 Median

63

66

64

 

 Range

35–89

42–89

35–83

 

 Mean

62.4

65.8

64.3

 

Staging

T

T1–T2

53 (29.8%)

26 (32.1%)

27 (27.8%)

1.00

T3–T4

19 (10.7%)

10 (12.3%)

9 (9.3%)

 

NA

106 (59.6%)

45 (55.6%)

61 (62.9%)

 

N

N0

34 (19.1%)

18 (22.2%)

16 (16.5%)

0.25

N1–3

42 (23.6%)

16 (19.8%)

26 (26.8%)

 

NA

102 (57.3%)

47 (58.0%)

55 (56.7%)

 

Stage

I–II

124 (69.7%)

62 (76.5%)

62 (63.9%)

0.10

III–IV

53 (29.8%)

19 (23.5%)

34 (35.1%)

 

NA

1 (0.56%)

0

1 (1.2%)

 
  1. Abbreviations: LZAP, leucine zipper-containing ARF-binding protein; NA, not available.
  2. Characteristics of patients whose tumors were included in the tissue microarray. Statistical analyses of patient groups were conducted by two-tailed Student’s t-test or Fisher’s exact test.